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Research and development

Decades of scientific research have given ALK-Abelló a leading position in the market for allergy vaccination. The company's core business is injection-based and drop-based allergy vaccines. In future the company will increasingly focus on tablet-based vaccines that give more patients access to convenient baseline treatment of their allergies.

In January and October 2005 ALK-Abelló presented a number of results from clinical studies of the company's tablet-based vaccine against grass pollen allergy, GRAZAX®. The findings are the latest in the series of favourable results which have successfully demonstrated and confirmed in recent years that GRAZAX® is an effective, safe and convenient treatment that improves patients’ quality of life. The application for regulatory approval of the tablet filed by ALK-Abelló with the Swedish authorities in June 2004 is still pending. ALK-Abelló’s expectation of being able to launch GRAZAX® on the first European markets in late 2006 is unchanged.

Pipeline
                       
Product type Active ingredient Indication Research Pre-clinical Phase I Phase II Phase III
GRAZAX® Biological grass pollen allergen Rhinit
Tablet Biological house dust mite allergen Rhinit/
asthma
Tablet Biological ragweed allergen Rhinit
Tablet Biological birch pollen allergen Rhinit
 
Recombinant allergy vaccine Rhinit/
asthma

Acquisitions and collaborations
ALK-Abelló is well prepared for the launch of these new tablet-based vaccines and the new marketing challenges which they entail. At the end of May 2005, ALK-Abelló's position was strengthened further by the acquisition of the French company Allerbio. France is the second-largest market for allergy vaccines after Germany.

The acquisition of Allerbio is a natural step in ALK-Abelló's further development to be the leader in research, development and production, as well as marketing and sales, in its particular niche.

See also

ALK-Abelló has teamed up with the Copenhagen University Hospital (Rigshospitalet) and NOVI Innovation A/S to start up a new company, T-Shift A/S.

In spring 2004 the Chinese health authorities gave ALK-Abelló the approval to market its injection-based vaccine Alutard SQ® againsthouse dust mite allergy in China.

 
Tablet against house dust mite allergy

ALK-Abelló initiated clinical tolerability studies of the tablet-based vaccine against house dust mite allergy in the autumn of 2005.